Efficient and convenient preparation of 3-aryl-2,2-dimethylpropanoates via Negishi coupling.
نویسندگان
چکیده
An efficient and convenient Negishi coupling protocol was developed for the preparation of 3-aryl-2,2-dimethylpropanoates providing easy access to key pharmaceutical intermediates that often require multi-step synthesis using conventional enolate chemistry.
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ورودعنوان ژورنال:
- Chemical communications
دوره 16 شماره
صفحات -
تاریخ انتشار 2009